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Find the best quality low-dose lithium supplement and get quality and cost comparisons for popular brands, including lithium orotate and lithium aspartate. This form of lithium binds lithium ions with aspartate ions and differs slightly from other forms such as lithium orotate. Most advocates of low-dose lithium therapy recommend them equally. Both Lithium orotate and lithium aspartate are supplements. Uscustomtees. *These statements have not been evaluated by the Food and Drug Administration. In addition, lithium promotes brain health by helping to inhibit over-activated N-methyl-D-aspartate (NMDA) receptors, which may lead to the impairment of brain cells. Swansonvitamins. ,As a dietary supplement, take one capsule per day with food and water. Lithium is a mineral that has long been used in the treatment of bipolar disorder, also known as manic depression.. Big Data + BI. 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